Episode guides from TV.com

1. Pilot
First aired: 7/22/2003
Writer: Ryan Murphy
Director: Ryan Murphy
Guest star: Roma Maffia (Liz Winters), Kelly Carlson (Kimberly Henry), Kelsey Lynn Batelaan (Annie McNamara), Ruth Williamson (Mrs. Grubman), Linda Klein (Nurse Linda) , Raymond Cruz (Alejandro), Robert LaSardo (Escobar Gallanto), Ara Celi (Celia), Geoffrey Rivas (Silvio Perez), Jeff Chase (Jose), Karla Hernandez (8 year old girl), Sal Lopez (Julio Esperanza), Rob Macie (Bartender), Grant Vaught (Young Christian), Marlene Forte, Joanna Sanchez

Old friends Sean (the family man) and Christian (the playboy) are partners in a plastic surgery office. Their relationship is under fire after Christian operates on a Colombian drug lord who pays him in drug money. Sean's family life is also in upheaval, and he is headed for a mid-life crisis.

2. Mandi/Randi
First aired: 7/29/2003
Writer: Ryan Murphy
Director: Ryan Murphy
Guest star: Nancy Cassaro (Suzanne), Kelsey Lynn Batelaan (Annie McNamara), Linda Klein (Nurse Linda), Roma Maffia (Liz Winters) , Kevin Chamberlin (Dr. Pendleton), Kate Mara (Vanessa), Caitlin Dahl (Mandi), Melinda Dahl (Randi), Sal Landi (Plumber), Noa Tishby (Jo), Katherine Disque (Temporary Anesthesiologist), Tim Elwell (Joel Brancato), Kerry Leigh Michaels (Waitress), Carmen Perez (Avanti)

Twin sisters want plastic surgery done to look different from each other. Sean moves out so he can experience life as a single man. Matt decides to try and perform a circumcision on himself after his girlfriend sees his penis. Christian is plagued with thoughts of Julia.

3. Nanette Babcock
First aired: 8/5/2003
Writer: Ryan Murphy
Director: Lawrence Trilling
Guest star: Linda Klein (Nurse Linda), Roma Maffia (Liz Winters), Ruth Williamson (Mrs. Grubman) , Sophia Bush (Ridley), Kate Mara (Vanessa), Eric Fleeks (Cop), Gina Marie Fields (Airport Security Guard), Javier Calderon, Michael Raysses, Edward Moss (Mr. Diamond), Lindsay Hollister (Nanette Babcock)

Sean and Julia discover Matt has tried to circumcise himself. The business is sued by a faithful client after Sean accidentally leaves a surgical tool inside of her body. Meanwhile, Christian and Grace struggle with a mentally unstable patient.

4. Sophia Lopez
First aired: 8/12/2003
Writer: Sean Jablonski
Director: Michael M. Robin
Guest star: Phillip Rhys (Jude), Joey Slotnick (Merril Bobolit), Linda Klein (Nurse Linda) , Jonathan Del Arco (Sophia Lopez), Patti D'Arbanville (Wallace Forsythe), Geoffrey Lewis (Marcus Grayson), Marnette Patterson (Fluffer), Brenda Strong (Isis), Tony Colitti (Male Nurse), Mark D. Espinoza (Ron), Jamie Hagan (Shyanne Summers), Catherine Dana Harrison (Marcy), Shana Orlando (Sunbather), Lucki Wheatino (Mrs. Kuzman)

Two recurring characters are introduced in an episode that teaches the odd-couple plastic surgeons a few lessons about moral boundaries. Patti D'Arbanville plays Wallis Forsythe, a pornography mogul who meets Christian at a party and agrees to send some business his way. And Joey Slotnick plays Merrill Bobolit, a hack surgeon who's more successful than Sean and Christian because of his willingness to take on any client. Forsythe's easy money and Bobolit's sleazy competition inject a dose of conflict into Sean and Christian's partnership--as if it needed any more of it!

5. Kurt Dempsey
First aired: 8/19/2003
Writer: Lynnie Greene, Richard Levine
Director: Elodie Keene
Guest star: Phillip Rhys (Jude), Roma Maffia (Liz Winters), Linda Klein (Nurse Linda) , Jessalyn Gilsig (Gina), Vincent Angell (Kurt Dempsey), Don McManus (David Collins), Brenda Strong (Isis), George Wyner (Doctor), John Marshall Jones (Victor), James Patrick Stuart (Serge), Valerie Wildman (Shelly Edwards), Stephanie Léon (Heidi Hollstrasser), Kristen Williams (Jasmine), Saemi Nakamera (Leigh Moriata), Gabrielle Carteris (Ellie Collins)

An ex-lover returns and leads Christian to a sexaholics meeting while Sean and Julia deal with an unexpected pregnancy.

6. Megan O'Hara
First aired: 9/2/2003
Writer: Jennifer Salt
Director: Craig Zisk
Guest star: Kelly Carlson (Kimberly Henry), Julie Warner (Megan O'Hara), Linda Klein (Nurse Linda) , Kate Mara (Vanessa), Leslie Grossman (Bliss Berger), Jessalyn Gilsig (Gina), David Barrera (Policeman), Rick Kelly (Jim O'Hara), Luis Antonio Ramos (Nico Scamarel), Harry Karp (Isaac), Sophia Bush (Ridley)

Someone is vandalizing Christian's possessions, and he attempts to find the culprit. A chemotherapy patient who is considering breast implants brings excitement to Sean's life, and Matt finds himself in a threesome with Vanessa and Riley.

7. Cliff Mantegna
First aired: 9/9/2003
Writer: Brad Falchuk
Director: Scott Brazil
Guest star: Kelly Carlson (Kimberly Henry), Phillip Rhys (Jude), Julie Warner (Megan O'Hara), Linda Klein (Nurse Linda) , Kate Mara (Vanessa), Alex Carter (Cliff Mantegna), Gerry Becker (Robert), Phina Oruche (Mia), Sydney Walsh (Alexi), Cyd Strittmatter, Belinda Waymouth, Joleigh Fioreavanti, Audra Wise, Sophia Bush (Ridley)

Christian's difficulties with Kristin are exacerbated when his feelings for Julia are revealed. Jude is hired as an intern, to sexy and disastrous results. Matt is caught mid-threesome by Julia.

8. Cara Fitzgerald
First aired: 9/16/2003
Writer: Ryan Murphy
Director: Jamie Babbit
Guest star: Julie Warner (Megan O'Hara), Kelsey Lynn Batelaan (Annie McNamara), Linda Klein (Nurse Linda) , Andrew Leeds (Henry), Alyson Reed (Kate Fitzgerald), Katy Selverstone (Devon Greco), Jamie McShane (Father Michael Shannon), Dorothy Lucey (News Anchor)

Mike accidentally hits Cara with his car, and assumes responsibility for her care when her religious parents refuse drugs and surgery. Christian finds that a patient used his face-changing surgery to hide a revolting crime.

9. Sophia Lopez II
First aired: 9/23/2003
Writer: Sean Jablonski
Director: Nelson McCormick
Guest star: Kelly Carlson (Kimberly Henry), Phillip Rhys (Jude), Joey Slotnick (Merril Bobolit), Julie Warner (Megan O'Hara), Roma Maffia (Liz Winters), Nancy Cassaro (Suzanne), Linda Klein (Nurse Linda) , Jonathan Del Arco (Sophia Lopez), Jazzmun (Transgendered Man), Kelly Mantle (Transgendered Man #2), Pam Green (Masseuse)

Sean and Jude's respective secrets are revealed, and Merril offers Christian an interesting trade: Kimber for a Lamborghini. Christian accepts, but Kimber discovers the truth and exacts a small revenge.

10. Adelle Coffin
First aired: 9/30/2003
Writer: Ryan Murphy, Dell Chandler
Director: Michael M. Robin
Story: Dell Chandler
Guest star: Joey Slotnick (Merril Bobolit), Julie Warner (Megan O'Hara), Ruth Williamson (Mrs. Grubman), Linda Klein (Nurse Linda), Roma Maffia (Liz Winters) , Clyde Kusatsu (Proctor Hiroshi), Jerry Hardin (Sumner Charles), Nan Martin (Adelle Coffin), Steven Anderson, Rick Kelly (Jim O'Hara), Jack Hannibal (Walter), Hamilton Mitchell (Ned), Jodi Taffel (Cindy), Darryl Theirse (Guard)

Sean and Christian learn that they have to take a test in order to continue practicing. Sean and Megan visit a doctor to learn that there is nothing they can do for her. Mrs. Grubman returns to get an operation on her and her fiance. Christian passes his test, but Sean walks out. Megan commits suicide. Julia finds out about Sean's affair with Megan.

11. Montana/Sassy/Justice
First aired: 10/7/2003
Writer: Lynnie Greene, Richard Levine
Director: Michael M. Robin
Guest star: Roma Maffia (Liz Winters), Kelsey Lynn Batelaan (Annie McNamara), Linda Klein (Nurse Linda) , L. Scott Caldwell, Jessalyn Gilsig (Gina), Andrew Leeds (Henry), Keri Lynn Pratt (Cara Fitzgerald), Ivonne Coll (Debbie), Cheryl White (Montana/Sassy/Justice Keane)

Ms. Caine wants an operation to get rid of her cankles. Sean and Julia are still on the outs. Christian learns he's going to be a father. Julia steals Christian's brush to determin if he's the father of Matt. Sean and Grace learn that Ms. Caine has multiple personalities. Cara recovers and gets close with Matt and Henry. Henry develops feelings for her. Cara asks Matt to the prom. Henry tells Matt that he is going to confess to Cara what happened.

12. Antonia Ramos
First aired: 10/14/2003
Writer: Jennifer Salt, Brad Falchuk
Director: Elodie Keene
Guest star: Jessalyn Gilsig (Gina Russo), Nancy Cassaro (Suzanne), Kelsey Lynn Batelaan (Annie McNamara), Roma Maffia (Liz Winters), Linda Klein (Nurse Linda) , Robert LaSardo (Escobar Gallardo), Jonathan Del Arco (Sophia Lopez), Marisol Nichols (Antonia Ramos), Daniel Zacapa (Pepe), Paul Cassell (Brad), Angelica Castro (María Amador), Susan Chuang (Pilates Instructor), Maritza Franco (Hard-bitten Girl), Darlena Tejeiro (Raquel), Darlene Dahl (Raquel)

Sean and Christian are reunited with an old friend, Julia bonds with Sofia Lopez, and Christian and Gina clash over their differences in opinion concerning Gina's pregnancy.

13. Escobar Gallardo
First aired: 10/21/2003
Writer: Ryan Murphy
Director: Ryan Murphy
Guest star: Kelly Carlson (Kimber Henry), Jessalyn Gilsig (Gina Russo), Kelsey Lynn Batelaan (Annie McNamara), Joey Slotnick (Merril Bobolit), Roma Maffia (Liz Winters) , Robert LaSardo (Escobar Gallardo), Ivonne Coll (Debbie), Ian Abercrombie (Mr. Parks), Daniel Zacapa (Pepe), Frank Noon (Pawnshop Owner), Ricki Lopez (Armand Ortiz / Jorge Barco), Gay Thomas-Wilson, Tom Virtue (FBI Agent)

Christian learns that Kimber and Merril are engaged. Escobar continues to have the surgeons do things for him. Liz is sent to Bermuda after being shot in the leg by one of Escobar's people. Sean goes to kill Escobar. Escobar makes a deal with Sean; a new face for their freedom. Christian learns, in the delivery room, that he is not the father of Gina's baby. Julia returns to get the paternity test she had done a while ago. The doctors do surgery on Escobar, and give him the face of a criminal even higher than Gallardo on the Most Wanted List - Armand Ortiz. Ortiz is arrested at the airport for bank robbing and killing a federal agent.